US

A new drug is making headlines around the world for being the first ever to slow the progression of Alzheimer’s disease. After an 18-month trial of 1,800 patients, lecanemab slowed patients’ mental decline by 27%. Although scientists are hailing a “new era” in treatment, strains on the NHS and the scale and complexity of the

Doctors have hailed a “new era” of medicine after a study showed for the first time that a drug can slow the debilitating symptoms of Alzheimer’s. Results from the clinical trial also revealed that the drug lecanemab cleared clumps of a protein called amyloid – thought to be a key cause of the most common

A woman who was abducted when she was a baby has been reunited with her family 51 years later. Melissa Highsmith went missing in 1971 when, at just 22 months old, she was taken by a babysitter from her parents’ Fort Worth, Texas, home. Melissa’s mother Alta Apantenco was working as a waitress and in

Former US vice president Mike Pence has criticised Donald Trump for dining with a Holocaust-denying white nationalist and the rapper formerly known as Kanye West. Mr Pence is among a number of Republicans calling on the former US president to apologise for what he has described as “profoundly poor judgement”. The group – Mr Trump,

An avowed white supremacist who carried out a deadly mass shooting at a supermarket in Buffalo has pleaded guilty to murder and hate-motivated terror charges. Payton Gendron, 19, drove for three hours from his home near Binghamton, New York state, to the Tops Friendly Markets store in Buffalo, where he opened fire with an AR-15-style

At some point in our lives most of us have done something to upset someone. That person might have responded by politely asking you not to do it again, or they may have decided life is too short and simply let it go. If you’re lucky they won’t have responded by paying a hitman thousands

A teenager has been denied permission to witness her father die by lethal injection in Missouri after a judge upheld a law that states she is too young. Kevin Johnson, 37, faces execution on Tuesday, 29 November for shooting a police officer in 2005, when he was 19. His daughter, Corionsa “Khorry” Ramey, was two

Elon Musk says he would support Republican Ron DeSantis if the Florida governor runs in the 2024 US presidential election race. Mr DeSantis was re-elected with nearly 60% of the vote in the midterms and has been tipped as a potential candidate to be the next US leader. Musk’s apparent endorsement of Mr DeSantis comes

The gunman in the Walmart mass shooting in Virginia left a “death note” addressed to God on his phone, police say. Andre Bing, 31, said that his actions were not planned, but things had fallen into place like he was being led by Satan, in the rambling note that was released by the Chesapeake Police Department

A man who fell from a cruise ship in the Gulf of Mexico has been rescued after more than 24 hours stranded in the water. The passenger on board Carnival Valor went missing at around 2.30pm local time on Wednesday, and – in a Thanksgiving holiday miracle – was not hoisted out of the water

Adidas is launching an investigation into allegations of misconduct against Kanye West, including claims he showed pornography and explicit images of Kim Kardashian to staff members. The German sportswear giant, which ended its partnership with the rapper last month, said it received an anonymous letter containing several allegations against the rapper. The independent probe follows

“Soccer’s coming home,” they sing, to the tune of the Skinner and Baddiel classic. It’s a chant of choice for American fans ahead of the World Cup showdown, poking fun at their English opponents. We heard it from the crowd watching the University of Maryland take on Fairleigh Dickinson University. The gag is, of course,

Police mugshots of the suspect in the attack on a Colorado LGBTQ venue have been released after the accused appeared in court for the first time. The images of Anderson Lee Aldrich, who was arrested in the aftermath of the mass shooting at the Q Club venue in Colorado Springs, were released by the city’s

Several people have died and others injured in a shooting at a Walmart store in Virginia, police say. It happened in the city of Chesapeake, with police called shortly after 10pm local time, spokesman officer Leo Kosinski said. “Chesapeake Police confirm an active shooter incident with fatalities at the Walmart on Sam’s Circle. The shooter

Six people have been killed after a Walmart employee opened fire at a store in Virginia. Police said a seventh person who died is believed to have been the gunman and four more victims are in hospital. It happened in the city of Chesapeake, with police called shortly after 10pm local time, spokesman officer Leo

The US Supreme Court has paved the way for the handover of former president Donald Trump’s tax returns to Congress after a three-year legal battle. The court rejected Mr Trump’s emergency application for an order that would have prevented the Treasury department from giving six years of tax returns for him and some of his

Carey Mulligan says meeting one of the New York Times’ reporters whose article brought down Harvey Weinstein “was rockstar crush stuff”. The film She Said shows the efforts that went into Megan Twohey and Jodi Kantor’s Pulitzer-prize winning journalism in 2017 which exposed Harvey Weinstein, then one of Hollywood’s most influential producers, as a sexual

Jay Leno has been pictured leaving hospital after being treated for facial burns he sustained in a garage fire. The former US talk show host, 72, said last week he’d been left with “serious burns from a gasoline fire” when one of his vintage cars burst into flames. Leno was pictured with staff from Grossman

Joe Biden is sending federal aid to western New York state to help authorities clean up after a massive storm dumped as much as 6ft of snow in western and northern areas. The emergency declaration authorises the US Department of Homeland Security and the Federal Emergency Management Agency to coordinate disaster relief in 11 counties

Most days there is an alert on my phone: the Washington DC police posting an update on the latest shooting in America’s capital city. ‘Shots fired’ ‘Suspect apprehended’ ‘Victim hospitalised’ Here’s the latest one, from the DC Police Department, from a few hours ago: “An arrest has been made and additional suspects are sought in

“Heroic people” confronted a gunman who killed five people at a gay nightclub in the US and stopped him killing any more, police have said. At least 18 others were injured at Club Q in the city of Colorado Springs. The suspect has been named as Anderson Lee Aldrich, 22, who was taken into custody

Donald Trump appears to be back on Twitter after an online poll voted for his return. The platform’s new owner Elon Musk had announced on Saturday evening that following the vote, the former president would be reinstated, almost two years after he was removed following the 6 January US Capitol riots. On hearing the news,

Facebook was encountering election interference content as far back as 2006, some 10 years before Mark Zuckerberg first acknowledged the issue, the platform’s former head of global public policy has claimed. Speaking at Sky News’ Big Ideas Live event, where experts and industry leaders discussed the biggest science and technology issues of our times, Paul

Disgraced Theranos founder Elizabeth Holmes has been sentenced to more than 11 years in a US federal prison for conning investors and endangering patients while peddling a bogus blood-testing technology. The 38-year-old was convicted by a Californian jury on three counts of investor fraud and one count of conspiracy in January. She was jailed for

Joe Biden has been accused of “capitulation” after his administration said Saudi Arabia’s crown prince should not face legal action over the murder of a US-based journalist. Despite the US president having previously vowed to make a “pariah” out of the country’s rulers following the 2018 killing of Jamal Khashoggi, the State Department has declared

Nancy Pelosi has said she will not run again to be Democratic leader in the House of Representatives, after nearly two decades in the role. The veteran politician lost the speakership after the Republicans took the House in the recent midterm elections. Despite saying she would step down from the role she has held since

The Republicans have won back control of the US House of Representatives. After two years of Democratic control of both the House and the Senate, the power dynamic in Washington will now shift. It means President Joe Biden‘s administration could struggle to enact parts of its legislative agenda. The Democrats did manage to keep control

Donald Trump may have declared that ”America’s comeback starts right now”, but the latest polls paint a questionable picture of his divisive re-election bid. The Republican Party’s lacklustre performance in the midterms and the failure of a string of Trump-endorsed candidates has many wondering if the former president is the right leader to challenge for the

“Don’t worry about the future, we’re in good hands.” So said former US president Bill Clinton in 2015, as he introduced Elizabeth Holmes to an adoring New York crowd. It seemed an uncontroversial statement at the time, as he hailed the achievements of a woman who had become America’s youngest self-made female billionaire after taking

Kari Lake, who backed Donald Trump’s false claims of voter fraud in 2020, has lost her bid to become the next governor of Arizona. The closely fought race with Democrat Katie Hobbs was one of the most significant in the US midterms as Arizona is a battleground state and is expected to play a pivotal role

Jay Leno was seriously burned after one of his cars burst into flames in the garage of his Los Angeles home. The US comedian was taken to hospital with facial burns after what his representative described as a “flash fire”. The 72-year-old former Tonight Show host cancelled a Las Vegas performance scheduled for Sunday night

US President Joe Biden has met his Chinese counterpart Xi Jinping and said they have a “responsibility” to show the two countries can “manage our differences”. Mr Xi went into the three-and-a-half-hour discussion prepared for a “candid and in-depth exchange of views” with Mr Biden, saying he hoped they would find areas of cooperation. And

Six people have been killed after two historic military planes collided during an airshow in the US city of Dallas. The planes – a B-17 Flying Fortress bomber and a P-63 Kingcobra fighter – crashed into each other at around 1.20pm local time. They were part of the Commemorative Air Force Wings Over Dallas show